Coding
Part:BBa_K2196001:Design
Designed by: Julianna Casella, Nicholas Roig, Chloe Savino, Jerin Thomas, Megan Schiesser, and Timothy Darby Group: iGEM17_Stony_Brook (2017-10-23)
Epidermicin NI01
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
Design Notes
When designing this insert, it was initially intended to be used in the pDB.His.X series plasmids and the pET-28 derived plasmid pTHST. The pDB.His.X series plasmids contain the T7 promoter, a 6xHis tag, followed by an expression tag (GST, MBP) and a TEV protease cleavage site. Expression of our insert can be induced by adding IPTG to a liquid culture of E. coli transformed with our construct. Since our construct already contained an expression tag, a promoter, and a RBS in the vector, these were not included in the design of our insert.
Source
Staphylococcus epidermidis strain 224